The manufacturers of this substance indicate that a single dose of MSM is very rarely effective and the supplement must be taken for at least 21 days or even longer to show any response. In fact they recommend that the higher the dose the better. For back pain, they recommend long term MSM therapy.
The major constituent of MSM is sulfur. Because sulfur is deemed safe there are no restrictions on the recommended dietary allowance. Thus, the manufacturers claim that one can take as much MSM as one wants. This will result in no complications but whether you benefit from it is another story. So far, only people who got suckered into buying this crap had back pain relief but now these individuals have mental problems.
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